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Hidden dynamic allostery in a PDZ domain

Structure–function relationships in proteins are predicated on the spatial proximity of noncovalently interacting groups of atoms. Thus, structural elements located away from a protein's active site are typically presumed to serve a stabilizing or scaffolding role for the larger structure. Here...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Petit, Chad M., Zhang, Jun, Sapienza, Paul J., Fuentes, Ernesto J., Lee, Andrew L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775317/
https://ncbi.nlm.nih.gov/pubmed/19828436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904492106
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