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Hidden dynamic allostery in a PDZ domain
Structure–function relationships in proteins are predicated on the spatial proximity of noncovalently interacting groups of atoms. Thus, structural elements located away from a protein's active site are typically presumed to serve a stabilizing or scaffolding role for the larger structure. Here...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775317/ https://ncbi.nlm.nih.gov/pubmed/19828436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904492106 |
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