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Ensemble-Based Analysis of the Dynamic Allostery in the PSD-95 PDZ3 Domain in Relation to the General Variability of PDZ Structures

PDZ domains are abundant interaction hubs found in a number of different proteins and they exhibit characteristic differences in their structure and ligand specificity. Their internal dynamics have been proposed to contribute to their biological activity via changes in conformational entropy upon li...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Dudola, Dániel, Hinsenkamp, Anett, Gáspári, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672539/
https://ncbi.nlm.nih.gov/pubmed/33172212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218348
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