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Ensemble-Based Analysis of the Dynamic Allostery in the PSD-95 PDZ3 Domain in Relation to the General Variability of PDZ Structures

PDZ domains are abundant interaction hubs found in a number of different proteins and they exhibit characteristic differences in their structure and ligand specificity. Their internal dynamics have been proposed to contribute to their biological activity <i>via</i> changes in conformatio...

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Main Authors: Dániel Dudola, Anett Hinsenkamp, Zoltán Gáspári
格式: Artigo
語言:Inglês
出版: MDPI AG 2020-11-01
叢編:International Journal of Molecular Sciences
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在線閱讀:https://www.mdpi.com/1422-0067/21/21/8348
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