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Conformational Dynamics and Cooperativity Drive the Specificity of a Protein-Ligand Interaction
Molecular recognition is critical for the fidelity of signal transduction in biology. Conversely, the disruption of protein-protein interactions can lead to disease. Thus, comprehension of the molecular determinants of specificity is essential for understanding normal biological signaling processes...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588728/ https://ncbi.nlm.nih.gov/pubmed/31146922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.05.008 |
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