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Conformational Dynamics and Cooperativity Drive the Specificity of a Protein-Ligand Interaction

Molecular recognition is critical for the fidelity of signal transduction in biology. Conversely, the disruption of protein-protein interactions can lead to disease. Thus, comprehension of the molecular determinants of specificity is essential for understanding normal biological signaling processes...

詳細記述

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書誌詳細
出版年:Biophys J
主要な著者: Liu, Xu, Golden, Lisa C., Lopez, Josue A., Shepherd, Tyson R., Yu, Liping, Fuentes, Ernesto J.
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588728/
https://ncbi.nlm.nih.gov/pubmed/31146922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.05.008
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