Tie2 and Eph Receptor Tyrosine Kinase Activation and Signaling

door Barton, William A., Dalton, Annamarie C., Seegar, Tom C.M., Himanen, Juha P., Nikolov, Dimitar B.
Gepubliceerd in 2014

Structural basis for regulation of ESCRT-III complexes by Lgd

door McMillan, Brian J., Tibbe, Christine, Drabek, Andrew, Seegar, Tom C. M., Blacklow, Stephen C., Klein, Thomas
Gepubliceerd in Cell Rep (2017)

Directed evolution provides insight into conformational substrate sampling by SrtA

door Suliman, Muna, Santosh, Vishaka, Seegar, Tom C. M., Dalton, Annamarie C., Schultz, Kathryn M., Klug, Candice S., Barton, William A.
Gepubliceerd in PLoS One (2017)

Extension of the Notch intracellular domain Ankyrin Repeat Stack by NRARP Promotes Feedback Inhibition of Notch Signaling

door Jarrett, Sanchez M., Seegar, Tom C. M., Andrews, Mark, Adelmant, Guillaume, Marto, Jarrod A., Aster, Jon C., Blacklow, Stephen C.
Gepubliceerd in Sci Signal (2019)

Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands

door Seegar, Tom C.M., Eller, Becca, Tzvetkova-Robev, Dorothea, Kolev, Momchil V., Henderson, Scott C., Nikolov, Dimitar B., Barton, William A.
Gepubliceerd in 2010

Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket

door Zimmerman, Brandon, Kelly, Brendan, McMillan, Brian J., Seegar, Tom C.M., Dror, Ron O., Kruse, Andrew C., Blacklow, Stephen C.
Gepubliceerd in Cell (2016)

Bispecific Forkhead transcription factor FoxN3 recognizes two distinct motifs with different DNA shapes

door Rogers, Julia M., Waters, Colin T., Seegar, Tom C.M., Jarrett, Sanchez M., Hallworth, Amelia N., Blacklow, Stephen C., Bulyk, Martha L.
Gepubliceerd in Mol Cell (2019)

Structural basis for angiopoietin-1–mediated signaling initiation

door Yu, Xuehong, Seegar, Tom C. M., Dalton, Annamarie C., Tzvetkova-Robev, Dorothea, Goldgur, Yehuda, Rajashankar, Kanagalaghatta R., Nikolov, Dimitar B., Barton, William A.
Gepubliceerd in 2013

Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10

door Seegar, Tom C.M., Killingsworth, Lauren B., Saha, Nayanendu, Meyer, Peter A., Patra, Dhabaleswar, Zimmerman, Brandon, Janes, Peter W., Rubinstein, Eric, Nikolov, Dimitar B., Skiniotis, Georgios, Kruse, Andrew C., Blacklow, Stephen C.
Gepubliceerd in Cell (2017)

Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases

door Adhikari, Arijit A., Seegar, Tom C. M., Ficarro, Scott B., McCurry, Megan D., Ramachandran, Deepti, Yao, Lina, Chaudhari, Snehal N., Ndousse-Fetter, Sula, Banks, Alexander S., Marto, Jarrod A., Blacklow, Stephen C., Devlin, A. Sloan
Gepubliceerd in Nat Chem Biol (2020)