Structural basis for angiopoietin-1–mediated signaling initiation

Angiogenesis is a complex cellular process involving multiple regulatory growth factors and growth factor receptors. Among them, the ligands for the endothelial-specific tunica intima endothelial receptor tyrosine kinase 2 (Tie2) receptor kinase, angiopoietin-1 (Ang1) and Ang2, play essential roles...

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Main Authors: Yu, Xuehong, Seegar, Tom C. M., Dalton, Annamarie C., Tzvetkova-Robev, Dorothea, Goldgur, Yehuda, Rajashankar, Kanagalaghatta R., Nikolov, Dimitar B., Barton, William A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645508/
https://ncbi.nlm.nih.gov/pubmed/23592718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216890110
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