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Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket
Tetraspanins comprise a diverse family of four-pass transmembrane proteins that play critical roles in the immune, reproductive, genitourinary, and auditory systems. Despite their pervasive roles in human physiology, little is known about the structure of tetraspanins or the molecular mechanisms und...
Tallennettuna:
Julkaisussa: | Cell |
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Päätekijät: | , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2016
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127602/ https://ncbi.nlm.nih.gov/pubmed/27881302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.056 |
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