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Antibodies binding the ADAM10 substrate recognition domain inhibit Eph function
The ADAM10 transmembrane metalloprotease cleaves a variety of cell surface proteins that are important in disease, including ligands for receptor tyrosine kinases of the erbB and Eph families. ADAM10-mediated cleavage of ephrins, the ligands for Eph receptors, is suggested to control Eph/ephrin-medi...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585520/ https://ncbi.nlm.nih.gov/pubmed/23108669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.112631 |
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