Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver

Hepatic flavin-containing mono-oxygenase 3 (FMO3) metabolizes a broad array of nucleophilic heteroatom (e.g., N or S)-containing xenobiotics (e.g., amphetamine, sulindac, benzydamine, ranitidine, tamoxifen, nicotine, and ethionamide), as well as endogenous compounds (e.g., catecholamine and trimethy...

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Detaylı Bibliyografya
Yayımlandı:J Pharmacol Exp Ther
Asıl Yazarlar: Xu, Meijuan, Bhatt, Deepak Kumar, Yeung, Catherine K., Claw, Katrina G., Chaudhry, Amarjit S., Gaedigk, Andrea, Pearce, Robin E., Broeckel, Ulrich, Gaedigk, Roger, Nickerson, Deborah A., Schuetz, Erin, Rettie, Allan E., Leeder, J. Steven, Thummel, Kenneth E., Prasad, Bhagwat
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2017
Konular:
Metabolism, Transport, and Pharmacogenomics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697103/
https://ncbi.nlm.nih.gov/pubmed/28819071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.243113
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