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Flavin oxidation in flavin‐dependent N‐monooxygenases

Siderophore A (SidA) from Aspergillus fumigatus is a flavin‐containing monooxygenase that hydroxylates ornithine (Orn) at the amino group of the side chain. Lysine (Lys) also binds to the active site of SidA; however, hydroxylation is not efficient and H(2)O(2) is the main product. The effect of pH...

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Détails bibliographiques
Publié dans:Protein Sci
Auteurs principaux: Robinson, Reeder M., Klancher, Catherine A., Rodriguez, Pedro J., Sobrado, Pablo
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295899/
https://ncbi.nlm.nih.gov/pubmed/30098072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3487
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