Genetic Variation in Aldo-Keto Reductase 1D1 (AKR1D1) Affects the Expression and Activity of Multiple Cytochrome P450s

Por Chaudhry, Amarjit S., Thirumaran, Ranjit K., Yasuda, Kazuto, Yang, Xia, Fan, Yiping, Strom, Stephen C., Schuetz, Erin G.
Publicado em 2013

In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice

Por Yasuda, Kazuto, Cline, Cynthia, Lin, Yvonne S., Scheib, Rachel, Ganguly, Samit, Thirumaran, Ranjit K., Chaudhry, Amarjit, Kim, Richard B., Schuetz, Erin G.
Publicado no Drug Metab Dispos (2015)

Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors

Por Tanner, Julie-Anne, Prasad, Bhagwat, Claw, Katrina G., Stapleton, Patricia, Chaudhry, Amarjit, Schuetz, Erin G., Thummel, Kenneth E., Tyndale, Rachel F.
Publicado no J Pharmacol Exp Ther (2017)

SUGP1 is a novel regulator of cholesterol metabolism

Por Kim, Mee J., Yu, Chi-Yi, Theusch, Elizabeth, Naidoo, Devesh, Stevens, Kristen, Kuang, Yu-Lin, Schuetz, Erin, Chaudhry, Amarjit S., Medina, Marisa W.
Publicado no Hum Mol Genet (2016)

Ontogeny and sorafenib metabolism

Por Zimmerman, Eric I., Roberts, Justin L., Li, Lie, Finkelstein, David, Gibson, Alice, Chaudhry, Amarjit S., Schuetz, Erin G., Rubnitz, Jeffrey E., Inaba, Hiroto, Baker, Sharyn D.
Publicado em 2012

Regulation of Coagulation Factor XI Expression by MicroRNAs in the Human Liver

Por Salloum-Asfar, Salam, Teruel-Montoya, Raúl, Arroyo, Ana B., García-Barberá, Nuria, Chaudhry, Amarjit, Schuetz, Erin, Luengo-Gil, Ginés, Vicente, Vicente, González-Conejero, Rocío, Martínez, Constantino
Publicado no PLoS One (2014)

The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles

Por Chaudhry, Amarjit S., Prasad, Bhagwat, Shirasaka, Yoshiyuki, Fohner, Alison, Finkelstein, David, Fan, Yiping, Wang, Shuoguo, Wu, Gang, Aklillu, Eleni, Sim, Sarah C., Thummel, Kenneth E., Schuetz, Erin G.
Publicado no Drug Metab Dispos (2015)

Human UGT1A4 and UGT1A3 Conjugate 25-Hydroxyvitamin D(3): Metabolite Structure, Kinetics, Inducibility, and Interindividual Variability

Por Wang, Zhican, Wong, Timothy, Hashizume, Takanori, Dickmann, Leslie Z., Scian, Michele, Koszewski, Nicholas J., Goff, Jesse P., Horst, Ronald L., Chaudhry, Amarjit S., Schuetz, Erin G., Thummel, Kenneth E.
Publicado em 2014

Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?([Image: see text])

Por Barr, John T., Choughule, Kanika V., Nepal, Sahadev, Wong, Timothy, Chaudhry, Amarjit S., Joswig-Jones, Carolyn A., Zientek, Michael, Strom, Stephen C., Schuetz, Erin G., Thummel, Kenneth E., Jones, Jeffrey P.
Publicado em 2014

Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism

Por Tracy, Timothy S., Chaudhry, Amarjit S., Prasad, Bhagwat, Thummel, Kenneth E., Schuetz, Erin G., Zhong, Xiao-bo, Tien, Yun-Chen, Jeong, Hyunyoung, Pan, Xian, Shireman, Laura M., Tay-Sontheimer, Jessica, Lin, Yvonne S.
Publicado no Drug Metab Dispos (2016)

Hepatic OATP Transporter and Thyroid Hormone Receptor Interplay Determines Cholesterol and Glucose Homeostasis

Por Meyer zu Schwabedissen, Henriette E., Ware, Joseph A., Finkelstein, David, Chaudhry, Amarjit S., Lemay, Sara, Leon-Ponte, Matilde, Strom, Stephen C., Zaher, Hani, Schwarz, Ute I., Freeman, David J., Schuetz, Erin G., Tirona, Rommel G., Kim, Richard B.
Publicado em 2011

CYP2C9*1B Promoter Polymorphisms, in Linkage with CYP2C19*2, Affect Phenytoin Autoinduction of Clearance and Maintenance Dose

Por Chaudhry, Amarjit S., Urban, Thomas J., Lamba, Jatinder K., Birnbaum, Angela K., Remmel, Rory P., Subramanian, Murali, Strom, Stephen, You, Joyce H., Kasperaviciute, Dalia, Catarino, Claudia B., Radtke, Rodney A., Sisodiya, Sanjay M., Goldstein, David B., Schuetz, Erin G.
Publicado em 2010