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Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
The cytochrome P450 (P450) enzymes are the predominant enzyme system involved in human drug metabolism. Alterations in the expression and/or activity of these enzymes result in changes in pharmacokinetics (and consequently the pharmacodynamics) of drugs that are metabolized by this set of enzymes. A...
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| 出版年: | Drug Metab Dispos |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767386/ https://ncbi.nlm.nih.gov/pubmed/26681736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.067900 |
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