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Isoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and Progesterone
Results from clinical studies suggest that pregnancy alters hepatic drug metabolism in a cytochrome P450 (P450) isoform-specific manner, and rising concentrations of female hormones are potentially responsible for the changes. The objective of this study was to comprehensively characterize the effec...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558868/ https://ncbi.nlm.nih.gov/pubmed/22837389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.046276 |
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