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Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism
AIMS: The plasma clearance of theobromine (TB; 3,7-dimethylxanthine) is known to be induced in cigarette smokers. To determine whether TB may serve as a model substrate for cytochrome P450 (CYP) 1A2, or possibly other isoforms, studies were undertaken to identify the individual human liver microsoma...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
1999
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014222/ https://ncbi.nlm.nih.gov/pubmed/10215755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00890.x |
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