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Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism

AIMS: The plasma clearance of theobromine (TB; 3,7-dimethylxanthine) is known to be induced in cigarette smokers. To determine whether TB may serve as a model substrate for cytochrome P450 (CYP) 1A2, or possibly other isoforms, studies were undertaken to identify the individual human liver microsoma...

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Hlavní autoři: Gates, Simon, Miners, John O
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014222/
https://ncbi.nlm.nih.gov/pubmed/10215755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00890.x
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