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Altered Cytochrome P450 Expression in Mice during Pregnancy

Human pregnancy is known to influence hepatic drug metabolism in a cytochrome (P450)-specific manner. However, the underlying mechanisms remain unknown, in part due to a lack of experimental models to study altered drug metabolism during pregnancy. In this study, we examined how pregnancy influences...

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Detalhes bibliográficos
Main Authors: Koh, Kwi Hye, Xie, Hui, Yu, Ai-Ming, Jeong, Hyunyoung
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033691/
https://ncbi.nlm.nih.gov/pubmed/20971892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.035790
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