DNA ligase IV guides end-processing choice during nonhomologous end joining

Nonhomologous end joining (NHEJ) must adapt to diverse end structures during repair of chromosome breaks. Here we investigate the mechanistic basis for this flexibility. DNA ends are aligned in a paired-end complex (PEC) by Ku, XLF, XRCC4, and DNA ligase IV (LIG4); we show by single-molecule analysi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Conlin, Michael P., Reid, Dylan A., Small, George W., Chang, Howard H., Watanabe, Go, Lieber, Michael R., Ramsden, Dale A., Rothenberg, Eli
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649367/
https://ncbi.nlm.nih.gov/pubmed/28930678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.091
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars