Sec17 (α-SNAP) and an SM-tethering complex regulate the outcome of SNARE zippering in vitro and in vivo

Zippering of SNARE complexes spanning docked membranes is essential for most intracellular fusion events. Here, we explore how SNARE regulators operate on discrete zippering states. The formation of a metastable trans-complex, catalyzed by HOPS and its SM subunit Vps33, is followed by subsequent zip...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Schwartz, Matthew L, Nickerson, Daniel P, Lobingier, Braden T, Plemel, Rachael L, Duan, Mengtong, Angers, Cortney G, Zick, Michael, Merz, Alexey J
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2017
विषय:
Biochemistry and Chemical Biology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643095/
https://ncbi.nlm.nih.gov/pubmed/28925353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27396
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