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Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes
At physiological protein levels, the slow HOPS- and SNARE-dependent fusion which occurs upon complete SNARE zippering is stimulated by Sec17 and Sec18:ATP without requiring ATP hydrolysis. To stimulate, Sec17 needs its central residues which bind the 0-layer of the SNARE complex and its N-terminal a...
Gorde:
| Argitaratua izan da: | eLife |
|---|---|
| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
eLife Sciences Publications, Ltd
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540461/ https://ncbi.nlm.nih.gov/pubmed/28718762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26646 |
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