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A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion
Membrane fusion requires priming, the disassembly of cis-SNARE complexes by the ATP-driven chaperones Sec18/17p. Yeast vacuole priming releases Vam7p, a soluble SNARE. Vam7p reassociation during docking allows trans-SNARE pairing and fusion. We now report that recombinant Vam7p (rVam7p) enters into...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514947/ https://ncbi.nlm.nih.gov/pubmed/15241469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600286 |
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