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A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion
Membrane fusion requires priming, the disassembly of cis-SNARE complexes by the ATP-driven chaperones Sec18/17p. Yeast vacuole priming releases Vam7p, a soluble SNARE. Vam7p reassociation during docking allows trans-SNARE pairing and fusion. We now report that recombinant Vam7p (rVam7p) enters into...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514947/ https://ncbi.nlm.nih.gov/pubmed/15241469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600286 |
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