Nalaganje...

Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes

At physiological protein levels, the slow HOPS- and SNARE-dependent fusion which occurs upon complete SNARE zippering is stimulated by Sec17 and Sec18:ATP without requiring ATP hydrolysis. To stimulate, Sec17 needs its central residues which bind the 0-layer of the SNARE complex and its N-terminal a...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Song, Hongki, Orr, Amy, Duan, Mengtong, Merz, Alexey J, Wickner, William
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540461/
https://ncbi.nlm.nih.gov/pubmed/28718762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26646
Oznake: Označite
Brez oznak, prvi označite!