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Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes

At physiological protein levels, the slow HOPS- and SNARE-dependent fusion which occurs upon complete SNARE zippering is stimulated by Sec17 and Sec18:ATP without requiring ATP hydrolysis. To stimulate, Sec17 needs its central residues which bind the 0-layer of the SNARE complex and its N-terminal a...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Song, Hongki, Orr, Amy, Duan, Mengtong, Merz, Alexey J, Wickner, William
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540461/
https://ncbi.nlm.nih.gov/pubmed/28718762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26646
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