Sec17 (α-SNAP) and an SM-tethering complex regulate the outcome of SNARE zippering in vitro and in vivo

Zippering of SNARE complexes spanning docked membranes is essential for most intracellular fusion events. Here, we explore how SNARE regulators operate on discrete zippering states. The formation of a metastable trans-complex, catalyzed by HOPS and its SM subunit Vps33, is followed by subsequent zip...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Schwartz, Matthew L, Nickerson, Daniel P, Lobingier, Braden T, Plemel, Rachael L, Duan, Mengtong, Angers, Cortney G, Zick, Michael, Merz, Alexey J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2017
Gaiak:
Biochemistry and Chemical Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643095/
https://ncbi.nlm.nih.gov/pubmed/28925353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27396
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