Tau exacerbates excitotoxic brain damage in an animal model of stroke

Neuronal excitotoxicity induced by aberrant excitation of glutamatergic receptors contributes to brain damage in stroke. Here we show that tau-deficient (tau(−/−)) mice are profoundly protected from excitotoxic brain damage and neurological deficits following experimental stroke, using a middle cere...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Bi, Mian, Gladbach, Amadeus, van Eersel, Janet, Ittner, Arne, Przybyla, Magdalena, van Hummel, Annika, Chua, Sook Wern, van der Hoven, Julia, Lee, Wei S., Müller, Julius, Parmar, Jasneet, Jonquieres, Georg von, Stefen, Holly, Guccione, Ernesto, Fath, Thomas, Housley, Gary D., Klugmann, Matthias, Ke, Yazi D., Ittner, Lars M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589746/
https://ncbi.nlm.nih.gov/pubmed/28883427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00618-0
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares