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Contribution of endogenous antibodies to learning deficits and astrocytosis in human P301S mutant tau transgenic mice
Antibodies have been explored extensively as a potential therapeutic for Alzheimer’s disease, where amyloid-β (Aβ) peptides and the tau protein deposit in patient brains. While the major focus of antibody-based therapy development was on Aβ, arguably with limited success in clinical trials, targetin...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7428012/ https://ncbi.nlm.nih.gov/pubmed/32796905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70845-x |
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