No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapt(tm1(EGFP)Kit) GFP Knockin Mice

Several mouse lines with knockout of the tau-encoding MAPT gene have been reported in the past; they received recent attention due to reports that tau reduction prevented Aβ-induced deficits in mouse models of Alzheimer’s disease. However, the effects of long-term depletion of tau in vivo remained c...

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Veröffentlicht in:PLoS One
Hauptverfasser: van Hummel, Annika, Bi, Mian, Ippati, Stefania, van der Hoven, Julia, Volkerling, Alexander, Lee, Wei S., Tan, Daniel C. S., Bongers, Andre, Ittner, Arne, Ke, Yazi D., Ittner, Lars M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063411/
https://ncbi.nlm.nih.gov/pubmed/27736877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163236
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