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No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapt(tm1(EGFP)Kit) GFP Knockin Mice

Several mouse lines with knockout of the tau-encoding MAPT gene have been reported in the past; they received recent attention due to reports that tau reduction prevented Aβ-induced deficits in mouse models of Alzheimer’s disease. However, the effects of long-term depletion of tau in vivo remained c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: van Hummel, Annika, Bi, Mian, Ippati, Stefania, van der Hoven, Julia, Volkerling, Alexander, Lee, Wei S., Tan, Daniel C. S., Bongers, Andre, Ittner, Arne, Ke, Yazi D., Ittner, Lars M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063411/
https://ncbi.nlm.nih.gov/pubmed/27736877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163236
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