Contribution of endogenous antibodies to learning deficits and astrocytosis in human P301S mutant tau transgenic mice

Antibodies have been explored extensively as a potential therapeutic for Alzheimer’s disease, where amyloid-β (Aβ) peptides and the tau protein deposit in patient brains. While the major focus of antibody-based therapy development was on Aβ, arguably with limited success in clinical trials, targetin...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: van der Hoven, Julia, van Hummel, Annika, Przybyla, Magdalena, Asih, Prita R., Gajwani, Mehul, Feiten, Astrid F., Ke, Yazi D., Ittner, Arne, van Eersel, Janet, Ittner, Lars M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428012/
https://ncbi.nlm.nih.gov/pubmed/32796905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70845-x
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