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Fluorescence polarization assays in high-throughput screening and drug discovery: a review

The sensitivity of Fluorescence Polarization (FP) and Fluorescence Anisotropy (FA) to molecular weight changes has enabled the interrogation of diverse biological mechanisms, ranging from molecular interactions to enzymatic activity. Assays based on FP/FA technology have been widely utilized in high...

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Bibliografske podrobnosti
izdano v:Methods Appl Fluoresc
Main Authors: Hall, Matthew D, Yasgar, Adam, Peryea, Tyler, Braisted, John C, Jadhav, Ajit, Simeonov, Anton, Coussens, Nathan P
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563979/
https://ncbi.nlm.nih.gov/pubmed/28809163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2050-6120/4/2/022001
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