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Fluorescence polarization assays in high-throughput screening and drug discovery: a review

The sensitivity of Fluorescence Polarization (FP) and Fluorescence Anisotropy (FA) to molecular weight changes has enabled the interrogation of diverse biological mechanisms, ranging from molecular interactions to enzymatic activity. Assays based on FP/FA technology have been widely utilized in high...

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Detalles Bibliográficos
Publicado en:Methods Appl Fluoresc
Main Authors: Hall, Matthew D, Yasgar, Adam, Peryea, Tyler, Braisted, John C, Jadhav, Ajit, Simeonov, Anton, Coussens, Nathan P
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563979/
https://ncbi.nlm.nih.gov/pubmed/28809163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2050-6120/4/2/022001
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