Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites

A series of analogues based on serine as lead structure were designed, and their agonist activities were evaluated at recombinant NMDA receptor subtypes (GluN1/2A–D) using two-electrode voltage-clamp (TEVC) electrophysiology. Pronounced variation in subunit-selectivity, potency, and agonist efficacy...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:ACS Chem Neurosci
Main Authors: Maolanon, Alex R., Risgaard, Rune, Wang, Shuang-Yan, Snoep, Yoran, Papangelis, Athanasios, Yi, Feng, Holley, David, Barslund, Anne F., Svenstrup, Niels, Hansen, Kasper B., Clausen, Rasmus P.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559341/
https://ncbi.nlm.nih.gov/pubmed/28514141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00117
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים