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Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors
NMDA receptors are ligand-gated ion channels that mediate excitatory neurotransmission in the brain and are involved in numerous neuropathological conditions. NMDA receptors are activated upon simultaneous binding of coagonists glycine and glutamate to the GluN1 and GluN2 subunits, respectively. Sub...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355950/ https://ncbi.nlm.nih.gov/pubmed/22553026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5757-11.2012 |
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