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Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors

NMDA receptors are ligand-gated ion channels that mediate excitatory neurotransmission in the brain and are involved in numerous neuropathological conditions. NMDA receptors are activated upon simultaneous binding of coagonists glycine and glutamate to the GluN1 and GluN2 subunits, respectively. Sub...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hansen, Kasper B., Ogden, Kevin K., Traynelis, Stephen F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355950/
https://ncbi.nlm.nih.gov/pubmed/22553026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5757-11.2012
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