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Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors

NMDA receptors are ligand-gated ion channels that mediate excitatory neurotransmission in the brain and are involved in numerous neuropathological conditions. NMDA receptors are activated upon simultaneous binding of coagonists glycine and glutamate to the GluN1 and GluN2 subunits, respectively. Sub...

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Detaylı Bibliyografya
Asıl Yazarlar: Hansen, Kasper B., Ogden, Kevin K., Traynelis, Stephen F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355950/
https://ncbi.nlm.nih.gov/pubmed/22553026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5757-11.2012
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