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Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors
NMDA receptors are ligand-gated ion channels that mediate excitatory neurotransmission in the brain and are involved in numerous neuropathological conditions. NMDA receptors are activated upon simultaneous binding of coagonists glycine and glutamate to the GluN1 and GluN2 subunits, respectively. Sub...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355950/ https://ncbi.nlm.nih.gov/pubmed/22553026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5757-11.2012 |
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