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The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine
Sarcosine is an amino acid involved in one-carbon metabolism and a promising therapy for schizophrenia because it enhances NMDA receptor (NMDAR) function by inhibiting glycine uptake. The structural similarity between sarcosine and glycine led us to hypothesize that sarcosine is also an agonist like...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727032/ https://ncbi.nlm.nih.gov/pubmed/19433577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.168757 |
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