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The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine

Sarcosine is an amino acid involved in one-carbon metabolism and a promising therapy for schizophrenia because it enhances NMDA receptor (NMDAR) function by inhibiting glycine uptake. The structural similarity between sarcosine and glycine led us to hypothesize that sarcosine is also an agonist like...

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Bibliografiske detaljer
Main Authors: Zhang, Hai Xia, Hyrc, Krzysztof, Thio, Liu Lin
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727032/
https://ncbi.nlm.nih.gov/pubmed/19433577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.168757
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