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The Glycine Transport Inhibitor Sarcosine Is an Inhibitory Glycine Receptor Agonist
Sarcosine is an endogenous amino acid that is a competitive inhibitor of the type I glycine transporter (GlyT1), an N-methyl-D-aspartate receptor (NMDAR) co-agonist, and an important intermediate in one-carbon metabolism. Its therapeutic potential for schizophrenia further underscores its clinical i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836904/ https://ncbi.nlm.nih.gov/pubmed/19619564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.07.019 |
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