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Mice thrive without Cdk4 and Cdk2

Mammalian cell division is thought to be driven by sequential activation of several Cyclin‐dependent kinases (Cdk), mainly Cdk4, Cdk6, Cdk2 and Cdk1. Since mice lacking Cdk4, Cdk6 or Cdk2 are viable, it has been proposed that they play compensatory roles. We report here that mice lacking Cdk4 and Cd...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Barrière, Cédric, Santamaría, David, Cerqueira, Antonio, Galán, Javier, Martín, Alberto, Ortega, Sagrario, Malumbres, Marcos, Dubus, Pierre, Barbacid, Mariano
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2007
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543859/
https://ncbi.nlm.nih.gov/pubmed/19383288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2007.03.001
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