Mice thrive without Cdk4 and Cdk2

Mammalian cell division is thought to be driven by sequential activation of several Cyclin‐dependent kinases (Cdk), mainly Cdk4, Cdk6, Cdk2 and Cdk1. Since mice lacking Cdk4, Cdk6 or Cdk2 are viable, it has been proposed that they play compensatory roles. We report here that mice lacking Cdk4 and Cd...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Barrière, Cédric, Santamaría, David, Cerqueira, Antonio, Galán, Javier, Martín, Alberto, Ortega, Sagrario, Malumbres, Marcos, Dubus, Pierre, Barbacid, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2007
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543859/
https://ncbi.nlm.nih.gov/pubmed/19383288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2007.03.001
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