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Role of recombination and replication fork restart in repeat instability

Eukaryotic genomes contain many repetitive DNA sequences that exhibit size instability. Some repeat elements have the added complication of being able to form secondary structures, such as hairpin loops, slipped DNA, triplex DNA or G-quadruplexes. Especially when repeat sequences are long, these DNA...

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Bibliografische gegevens
Gepubliceerd in:DNA Repair (Amst)
Hoofdauteurs: Polleys, Erica J., House, Nealia C.M., Freudenreich, Catherine H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541998/
https://ncbi.nlm.nih.gov/pubmed/28641941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.018
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