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NuA4 initiates dynamic histone H4 acetylation to promote high-fidelity sister chromatid recombination at post-replication gaps

CAG/CTG trinucleotide repeats are unstable, fragile sequences that strongly position nucleosomes, but little is known about chromatin modifications required to prevent genomic instability at these or other structure-forming sequences. We discovered that regulated histone H4 acetylation is required t...

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Detalhes bibliográficos
Main Authors: House, Nealia C.M., Yang, Jiahui H., Walsh, Stephen C., Moy, Jonathan M., Freudenreich, Catherine H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169719/
https://ncbi.nlm.nih.gov/pubmed/25132173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.07.007
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