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Genetic assays to study repeat fragility in Saccharomyces cerevisiae
Trinucleotide repeats are common in the human genome and can undergo changes in repeat number and cause length-dependent chromosome fragility. Expanded CAG repeats have been linked to over 14 human diseases and are considered hotspots for breakage and genomic rearrangement. Here we describe two Sacc...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7181387/ https://ncbi.nlm.nih.gov/pubmed/31586342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9784-8_5 |
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