Double-Strand Break Repair Pathways Protect against CAG/CTG Repeat Expansions, Contractions and Repeat-Mediated Chromosomal Fragility in Saccharomyces cerevisiae

Trinucleotide repeats can form secondary structures, whose inappropriate repair or replication can lead to repeat expansions. There are multiple loci within the human genome where expansion of trinucleotide repeats leads to disease. Although it is known that expanded repeats accumulate double-strand...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Sundararajan, Rangapriya, Gellon, Lionel, Zunder, Rachel M., Freudenreich, Catherine H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2010
Onderwerpen:
Investigations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815931/
https://ncbi.nlm.nih.gov/pubmed/19901069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.111039
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items