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Postreplication Repair Inhibits CAG · CTG Repeat Expansions in Saccharomyces cerevisiae
Trinucleotide repeats (TNRs) are unique DNA microsatellites that can expand to cause human disease. Recently, Srs2 was identified as a protein that inhibits TNR expansions in Saccharomyces cerevisiae. Here, we demonstrate that Srs2 inhibits CAG · CTG expansions in conjunction with the error-free bra...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800661/ https://ncbi.nlm.nih.gov/pubmed/17060452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01167-06 |
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