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Role of recombination and replication fork restart in repeat instability

Eukaryotic genomes contain many repetitive DNA sequences that exhibit size instability. Some repeat elements have the added complication of being able to form secondary structures, such as hairpin loops, slipped DNA, triplex DNA or G-quadruplexes. Especially when repeat sequences are long, these DNA...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Polleys, Erica J., House, Nealia C.M., Freudenreich, Catherine H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541998/
https://ncbi.nlm.nih.gov/pubmed/28641941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.018
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