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Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks

The DNA replication or S-phase checkpoint monitors the integrity of DNA synthesis. Replication stress or DNA damage triggers fork stalling and checkpoint signaling to activate repair pathways. Recovery from checkpoint activation is critical for cell survival following DNA damage. Recovery from the S...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chaudhury, Indrajit, Koepp, Deanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389566/
https://ncbi.nlm.nih.gov/pubmed/27956499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1249
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