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Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks
The DNA replication or S-phase checkpoint monitors the integrity of DNA synthesis. Replication stress or DNA damage triggers fork stalling and checkpoint signaling to activate repair pathways. Recovery from checkpoint activation is critical for cell survival following DNA damage. Recovery from the S...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389566/ https://ncbi.nlm.nih.gov/pubmed/27956499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1249 |
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