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FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery

Fanconi Anemia (FA) and Bloom Syndrome share overlapping phenotypes including spontaneous chromosomal abnormalities and increased cancer predisposition. The FA protein pathway comprises an upstream core complex that mediates recruitment of two central players, FANCD2 and FANCI, to sites of stalled r...

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Detalhes bibliográficos
Main Authors: Chaudhury, Indrajit, Sareen, Archana, Raghunandan, Maya, Sobeck, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711430/
https://ncbi.nlm.nih.gov/pubmed/23658231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt348
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