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FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery

Fanconi Anemia (FA) and Bloom Syndrome share overlapping phenotypes including spontaneous chromosomal abnormalities and increased cancer predisposition. The FA protein pathway comprises an upstream core complex that mediates recruitment of two central players, FANCD2 and FANCI, to sites of stalled r...

詳細記述

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書誌詳細
主要な著者: Chaudhury, Indrajit, Sareen, Archana, Raghunandan, Maya, Sobeck, Alexandra
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711430/
https://ncbi.nlm.nih.gov/pubmed/23658231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt348
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