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FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response
Fanconi anemia (FA) is an inherited cancer predisposition syndrome characterized by cellular hypersensitivity to DNA interstrand crosslinks (ICLs). To repair these lesions, the FA proteins act in a linear hierarchy: following ICL detection on chromatin, the FA core complex monoubiquitinates and recr...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714191/ https://ncbi.nlm.nih.gov/pubmed/29059323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx847 |
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