FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response

Fanconi anemia (FA) is an inherited cancer predisposition syndrome characterized by cellular hypersensitivity to DNA interstrand crosslinks (ICLs). To repair these lesions, the FA proteins act in a linear hierarchy: following ICL detection on chromatin, the FA core complex monoubiquitinates and recr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Thompson, Elizabeth L., Yeo, Jung E., Lee, Eun-A, Kan, Yinan, Raghunandan, Maya, Wiek, Constanze, Hanenberg, Helmut, Schärer, Orlando D., Hendrickson, Eric A., Sobeck, Alexandra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Molecular Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714191/
https://ncbi.nlm.nih.gov/pubmed/29059323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx847
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