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CtIP mediates replication fork recovery in a FANCD2-regulated manner
Fanconi anemia (FA) is a chromosome instability syndrome characterized by increased cancer predisposition. Within the FA pathway, an upstream FA core complex mediates monoubiquitination and recruitment of the central FANCD2 protein to sites of stalled replication forks. Once recruited, FANCD2 fulfil...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065146/ https://ncbi.nlm.nih.gov/pubmed/24556218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu078 |
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